Midtown (77006, 77004)
Main Reasons People Live in Midtown:

Full of hip single professionals.
Lowest rent in the inner loop.
METRORail runs through Midtown to Downtown, Texas Medical Center for work; to Rice University for school; or to entertainment at: the famous Hermann Park & Reliant Park (4 major professional sports stadiums and exhibition areas) -  giving you access [...]

Downtown (77002, 77010)
Main Reasons People Live in Downtown:

Convenient to get to Downtown work
Lower priced than other Inner Loop areas
Revived restaurants, shopping areas, landscaping and housing.
If you work anywhere else, you go against the traffic flow and save time.
Walking lifestyle with its underground tunnel system full of a generous variety of useful shops and the METRORail [...]

Before You Move
In this section, we want to give helpful hints to those who are renting. Read this section before you go to select your new residence. It will save you time and money.
A. Renting
While renting in Houston , you’ll have the choice of apartment, loft or townhome. Currently, the most sought after trend is [...]

Galleria/Uptown (77056, 77057, 77027)
“Inner Loop ” Areas Map of HOUSTON
Copyright 2010 – ApartmentSneakPeeks
Main Reasons People Live in Galleria/Uptown:

Premier dining and entertainment area of Houston .
Most exciting social scene in Houston for successful professionals of any age.
Walk to entertainment lifestyle (restaurants and night life all around)
Choose inner or outer loop living depending on where you work.
Traffic [...]